中国科学院上海巴斯德研究所是由中国科学院、上海市政府、法国巴斯德研究所三方共建的科学研究机构，面向国家传染病预防与控制的重大需求和国际前沿，围绕重大传染性疾病的致病机制、免疫应答规律及防治策略，开展基础和应用型研究，教育和培养创新型人才。 

　　上海巴斯德所虫媒病毒研究组课题组以新发突发病毒如流感病毒以及登革热等虫媒病毒为主要研究对象，这些病毒给公共卫生和安全带来了巨大的威胁，关于这些病毒在细胞和分子水平上的细胞嗜性和致病机理仍存在很多未知。我们通过体内外实验，揭示病毒致病因子、宿主促病毒因子或者限制性因子。 

　　岗位描述： 

　　现招聘博士后1名，2年固定合约，待遇从优，根据课题和项目情况决定是否延期。 

　　1）开展新发突发虫媒病毒性传染病致病机制的课题研究。 

　　2）建立蚊虫病毒体内外感染模型。 

　　3）研究限制性宿主因子在病毒复制和疫情传播中的作用。 

　　应聘条件： 

　　1）需具备病毒学或相关专业博士学位。 

　　2）具有扎实的病毒学研究背景，熟练掌握分子病毒学、分子生物学、细胞生物学实验技术；具有CRISPR/Cas9基因编辑技术和蚊虫实验经验者优先。 

　　3）工作认真踏实，有高度的责任心、进取心和主动性；乐于学习新知识与新技术。 

　　4）富有团队合作精神和良好的人际沟通能力，有较强的英文交流和读写能力，协作能力强。 

　　5）需以第一作者发表过一篇或以上SCI收录的论文。 

　　应聘方式：  

　　请应聘者将本人简历(Curriculum vitae)、自荐信和推荐人联系方式通过电子邮件发送至Prof. Dimitri Lavillette(dlaville@ips.ac.cn)和徐老师kxu@sibs.ac.cn，邮件标题请注明应聘岗位。对符合要求者将尽快安排面试。应聘者资料恕不退还，招聘单位将予以严格保密。  

    本招聘启示至招聘岗位招满前一直有效。

　　Post-doctoral position in Arbovirus group open at IPS, Shanghai, PR China 

　　IPS(Institut Pasteur of Shanghai) is the first international institute under the Chinese Academy of Sciences (CAS). Founded in 2004 by CAS, the Institut Pasteur and the Shanghai Municipal Government, IPS is an independent, nonprofit life sciences institute that works closely with Chinese authorities to address public health problems. IPS creates synergies between the Institut Pasteur and CAS networks, leveraging all the assets of Shanghai, one of Asia’s leading business and technology hubs. IPS is engaged in broad research related to infectious diseases, including basic research, epidemiological investigation and vaccine research on HIV, viral hepatitis B and C, respiratory viruses, cancer-related viruses, zoonotic viruses (including mosquito-borne viruses), malaria, etc. Together with its academic and industry partners, IPS’s goal is to develop diagnostic, vaccine and therapeutic products to meet the challenges of emerging and re-emerging infectious diseases.  

　　In group of Arbovirus, by studying both infections in mammals and insects, our global project wants to unveil the viral and/or host factors responsible for pathogenicity or resistance to infection. Using different model alphaviruses (Chikungunya…) and Flaviviruses (Dengue, Zika…), we want to explore: i) the host factors involved in entry, interspecies transmission and host susceptibility; and ii) the role of cell response in virus replication and the spreading of viruses in vivo. These understanding will help to develop new strategies to fight these public health and veterinary threats.  

　　Job description: 

　　This is a full-time, fixed-term position available for up to 2 years, with the possibility of extension subject to the availability of funding. The work mainly includes: 

　　1.Pathogenesis study of emerging and re-emerging arboviruses.  

　　2.Establish in vivo and in vitro mosquitoes infection models. 

　　3.Study the role of host factor in virus replication and disease outbreak.  

　　Candidates: 

　　The successful candidate must be in possession of a PhD in Biological Sciences (mention Virology, mosquito genetics or cell biology). You must have a high level of expertise and skills in synthetic biology, molecular genetics and cloning. A demonstrable experience in working with genome editing technologies including CRISPR/Cas9 will be desirable. Demonstrable experience of working with mosquitoes would be desirable, as well as a good knowledge of insect biology, genetics and transgenesis. 

　　You must be a highly motivated, innovative and creative inpidual with demonstrable ability to develop and apply new concepts, and a proactive approach to problem solving. The successful candidate must be able to organise and prioritise their own work with minimal supervision and to independently drive forward their research project. Good verbal and written communication skills in English, and proven ability to write clearly and succinctly for high profile publications are also essential.  

　　Emerging successful track record of academic publications commensurate with experience. 

　　Application:  

　　Candidates are invited to contact Prof. Dimitri LAVILLETTE (dlaville@ips.ac.cn) and Dr. Ke Xu (kxu@sibs.ac.cn) for further details. Please send an application with the following: - Cover letter - Concise summary of previous research activities - Curriculum vitae including publication list and contact details for 2-3 referrals 

来源：

http://www.shanghaipasteur.cas.cn/zp/zpxx/qtgw/201703/t20170301_4753446.html